Journal article
Electrochemical and mechanical performance of reduced graphene oxide, conductive hydrogel, and electrodeposited Pt-Ir coated electrodes: An active in vitro study
AN Dalrymple, M Huynh, UA Robles, JB Marroquin, CD Lee, A Petrossians, JJ Whalen, D Li, HC Parkington, JS Forsythe, RA Green, LA Poole-Warren, RK Shepherd, JB Fallon
Journal of Neural Engineering | IOP PUBLISHING LTD | Published : 2020
Abstract
Objective. To systematically compare the in vitro electrochemical and mechanical properties of several electrode coatings that have been reported to increase the efficacy of medical bionics devices by increasing the amount of charge that can be delivered safely to the target neural tissue. Approach. Smooth platinum (Pt) ring and disc electrodes were coated with reduced graphene oxide, conductive hydrogel, or electrodeposited Pt-Ir. Electrodes with coatings were compared with uncoated smooth Pt electrodes before and after an in vitro accelerated aging protocol. The various coatings were compared mechanically using the adhesion-by-tape test. Electrodes were stimulated in saline for 24 hours/da..
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Awarded by NHMRC of the Australian Government
Funding Acknowledgements
This work was funded by the NHMRC of the Australian Government (APP1122055) and the Garnett Passe and Rodney Williams Memorial Foundation for which we are most grateful. The Bionics Institute acknowledges support of the Victorian Government through Operational Infrastructure Support Program. We thank Dr A Thompson, C McGowan, V Maxim, H Feng, J Zhou, and R Thomas from the Bionics Institute, R Curtain and the SEM Facility at Bio21, the University of Melbourne for their excellent technical assistance, and staff at the National Measurement Institute of the Australian Government for ICP-MS analysis. We also thank Dr S Cogan and EIC Laboratories Inc. (USA) for providing us with the IrO<INF>2</INF> samples. Platinum Group Coatings (PGC) acknowledges the support of the Pasadena Bioscience Collaborative and thank J Sharkey and G Weiland for preparing test samples. We also thank Dr P Carter from Cochlear Ltd. for his valuable input on the manuscript.